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KYGENESIS®

Kidney Advance®

Supports whole-body balance and healthy kidney function with time-tested formula. Formulated to target systemic inflammation, support circulation, assist detox pathways, and reduce oxidative stress-critical for protecting kidneys over time.^†

Kidney Prime®
Herbal kidney protection - blood flow, inflammation, and kidney tissue support.
Add to cart $59.00 USD$44.25 USD

Can I cancel my subscription anytime?

Yes—absolutely. You’re in full control. You can cancel your subscription at any time, but please make sure to do so at least 3 days before your next scheduled payment to avoid being charged for the upcoming month. This gives our team enough time to process the request smoothly. If you need help, our support team is always here to assist.

Benefits of KYGENESIS® Kidney Advance®

Advanced Kidney Function Support
Designed to complement Kidney Prime® with additional herbs and nutrients that target specific kidney pathways for optimal function.^†
Help Normalize Blood Pressure & Flow
It supports healthy circulation and pressure, which are key factors in long-term kidney protection.^†
Regulate Mineral Balance
Includes ingredients that help maintain ideal levels of calcium, phosphate, and sodium without overburdening the kidneys.^†
Slow Fibrosis & Tissue Scarring
Combats the slow scarring of kidney tissue, often seen in progressive kidney disease.^†
Encourage Tissue Repair and Regeneration
Herbal compounds stimulate the natural repair mechanisms of kidney cells and glomeruli.^†
Support Blood Sugar Metabolism
Helps regulate glycation, insulin signaling, and blood sugar, factors that deeply affect kidney health.^†

Whether you’re managing early warning signs or navigating chronic concerns, KYGENESIS® Kidney Advance® helps strengthen your body’s natural defense against kidney decline. Taking control starts with the right daily support.^†

Suggested Use

Take 1 capsule twice daily, with meals (e.g., breakfast and dinner). Supports absorption of herbal actives and reduces the chance of GI sensitivity.^†

Science-Based Formula

Made in the USA with domestic and imported ingredients.
Manufactured in a GMP-Certified Facility
Formulated with Non-GMO Ingredients
100% Vegan-Friendly
Manufactured in an FDA-Registered Facility

Antioxidant

Kidneys

Blood Sugar^†

Cardio Health^†

Cellular Energy^†

What’s inside matters:  
Targeted support for kidney strength and resilience

KYGENESIS® Kidney Advance® is carefully chosen to deliver intensive, full-spectrum support for long-term kidney resilience. This advanced formula combines anti-inflammatory botanicals, circulation-enhancing compounds, and antioxidant defenders to help ease filtration burden, strengthen detox pathways, and protect kidney tissue from progressive stress.^†

R-Alpha Lipoic Acid

(R-ALA)

N-Acetyl-L-Cysteine

(NAC)

Ubiquinol

(Active CoQ10)

BioPerine®

Black Pepper Fruit Extract

Serving Size: 1 capsule; Servings Per Container: 60

Amount Per Serving % DV
R-Alpha Lipoic Acid 200mg *
N-Acetyl-L-Cysteine 200mg *
Ubiquinol (Active CoQ10) 150mg *
BioPerine® Black Pepper Fruit Extract 5mg *

*Daily value (DV) not established.

Take 1 capsule twice daily, with meals (e.g., breakfast and dinner). Supports absorption of herbal actives and reduces the chance of GI sensitivity.^†

KYGENESIS® Kidney Advance® is a comprehensive formula designed to defend kidney health at the cellular level.

It helps ease inflammation, support healthy filtration, and protect against oxidative damage, three key factors in slowing kidney decline and building long-term resilience.^†

Kidney Advance® delivers targeted support to the kidneys while also promoting whole-body balance—from immune health and detoxification to healthy energy and resilience.^†

At KYGENESIS®, we’re committed to exceptional quality—sourcing premium raw materials, performing rigorous testing, and creating potent, kidney-safe formulas that support long-term wellness.^†

Store in a cool, dry place. Consult your health care professional before use if you are pregnant or nursing, have or had a medical condition, or are taking any medication. Do not use if seal is broken or missing. Keep out of reach of children.

Science-Based Formula

Made in the USA with domestic and imported ingredients.

Manufactured in a GMP-Certified Facility

Formulated with Non-GMO Ingredients 100% Vegan-Friendly

Manufactured in an FDA-Registered Facility

How KYGENESIS® Kidney Advance®
Compares to other supplements

Many supplements claim to support kidneys, but few offer the comprehensive, whole-body approach of Kidney Advance®. Designed to target systemic inflammation, detoxification, immune health, and circulation, this formula delivers multi-layered support for long-term kidney protection—where most others fall short.^†

Regular supplements

Another supplements

KYGENESIS®  Kidney Advance®

Clinically Recommended for all Kidney Stages†^†

Broad-spectrum kidney protection and resilience^†

Contains adaptogens and botanicals^†

Gentle on Digestion, Potassium-Free

Includes Research-Backed Herbal Extracts^†

Formulated by Kidney Naturopaths

Add To Cart

Common questions: About KYGENESIS® Kidney Alkalizing Formula

Curious how this herbal blend supports long-term kidney strength and inflammation reduction? You’re not alone—here’s what others are asking.

What is KYGENESIS® Kidney Advance® designed to do?

KYGENESIS® Kidney Advance® is designed to strengthen whole-body balance and long-term kidney function through targeted, multi-system support. Its carefully selected ingredients help calm systemic inflammation, support detox pathways, and defend kidney cells from ongoing oxidative stress, making it ideal for those seeking deeper, sustained kidney protection.^†

Is it safe to take with my current medications?

Yes, many people take this blend alongside standard medications. However, some herbs and nutrients may interact with prescription drugs, so we always recommend consulting your doctor or pharmacist before starting any new product—especially if you’re managing multiple conditions.

How long before I notice results?

While everyone is different, many customers begin to feel subtle improvements in energy, clarity, or digestion within the first few weeks. Lab results such as eGFR or creatinine may show changes in 8–12 weeks of consistent use, especially when paired with dietary and lifestyle changes.^†

Is this formula safe for long-term use?

Yes, KYGENESIS® Kidney Advance® is formulated for ongoing support and is safe to take daily. The ingredients have a strong safety profile and are suitable for extended use unless otherwise advised by your healthcare provider.^†

Does it replace a kidney diet or other supplements?

Not at all. Think of these capsules as a powerful addition to your kidney wellness plan—not a replacement. They work best when combined with a kidney-friendly diet, proper hydration, and other supportive tools like the KYGENESIS® system or Kidney Coach programs.

Can I take it with other KYGENESIS® supplements?

Absolutely. Kidney Advance® was designed to complement the other formulas in the KYGENESIS® line, especially Kidney Prime®, Gluco Restore™, and the Alkalizing Formula. You can take them together or space them out through the day, based on your routine and your practitioner’s guidance.^†

What do extract ratios like 10:1 or 4:1 mean, and how much herb am I getting?

Extract ratios tell you how much raw plant material was used to produce the final, concentrated extract. The higher the ratio, the more concentrated the extract.

A 10:1 extract means 10 parts of raw herb were used to make 1 part of extract. So if your supplement contains 100 mg of a 10:1 extract, it’s equivalent to 1,000 mg (1 gram) of the whole herb.

A 4:1 extract means 4 parts of raw herb become 1 part of extract. So if your supplement contains 100 mg of a 4:1 extract, that equals 400 mg of the raw herb.

These concentrated extracts allow you to get the full benefit of therapeutic doses, without needing to take large quantities. They also ensure better consistency, quality, and potency from capsule to capsule.