


Kidney Prime®
Daily foundational kidney support with proven formula. Designed to strengthen kidney resilience, normal creatinine levels, and help protect filtration capacity from daily stress and inflammation and rejuvenates kidney function.†
Can I cancel my subscription anytime?
Yes—absolutely. You’re in full control. You can cancel your subscription at any time, but please make sure to do so at least 3 days before your next scheduled payment to avoid being charged for the upcoming month. This gives our team enough time to process the request smoothly. If you need help, our support team is always here to assist.
Benefits of KYGENESIS® Kidney Prime®
- Strengthen Filtration and Kidney Function
This comprehensive herbal blend is formulated to fortify the kidneys’ natural filtration processes, helping maintain healthy eGFR and creatinine levels.†
- Herbal Adaptogens for Stress and Immunity
Contains adaptogenic botanicals that modulate stress and support immune balance, protecting the kidneys from internal and external stressors.†
- Boost Antioxidant Defense
Powerful antioxidant ingredients help neutralize damaging free radicals, which can otherwise contribute to long-term kidney deterioration.†
- Reduce Inflammatory Load
It supports the body's inflammatory response with plant-based compounds that have been shown to calm immune overactivation and promote tissue healing.†
- Promote Natural Detoxification
Enhances the elimination of metabolic waste, working synergistically with the body’s natural detox pathways.†
- Trusted by Thousands Worldwide
KYGENESIS® Kidney Prime® is a foundational product in our protocol, backed by countless success stories and practitioner recommendations.†
- Gentle and Potent
Crafted to deliver maximum results with minimal disruption—suitable even for sensitive kidneys.†
No matter where you are on your health journey, it’s never too late — or too early — to support your kidneys. With the right nutrients, herbs, and daily habits, you can protect kidney function and give your body what it needs to thrive naturally.†
Suggested Use
Take 2 capsules twice daily with food, or as directed by your healthcare professional.†
Science-Based Formula
Made in the USA with domestic and imported ingredients.
Manufactured in a GMP-Certified Facility
Formulated with Non-GMO Ingredients
100% Vegan-Friendly
Manufactured in an FDA-Registered Facility
Immunity†
Kidneys
Anti-Aging†
Cardio Health†
Energy†
What’s inside matters:
Foundational nutrients for whole-body kidney wellness.
KYGENESIS® Kidney Prime® delivers essential vitamins, minerals, and antioxidants designed to strengthen kidney resilience from the ground up. With ingredients known to reduce inflammation, support detox pathways, and promote healthy circulation, this formula provides daily foundational care for the kidneys—backed by decades of clinical research.†
Fo-Ti
(Polygonum multiflorum) Root Extract 4:1
Fo-Ti is a revered root in traditional Chinese medicine known for its restorative properties and support of kidney, liver, and longevity systems†. Often used to “nourish the kidneys” and support healthy aging, Fo-Ti contains antioxidant compounds like stilbene glycosides that help defend against cellular damage and oxidative stress. Modern research suggests Fo-Ti may help protect renal function by supporting healthy mitochondrial activity and reducing markers of fibrosis. This 4:1 extract offers a concentrated form of its rejuvenating benefits—ideal for those seeking foundational kidney and vitality support.
Tienchi Ginseng
(Panax notoginseng) Root Extract 4:1
Tienchi Ginseng is a prized adaptogenic root traditionally used to support circulation, reduce inflammation, and protect delicate vascular networks like those in the kidneys†. Unlike common ginsengs, Tienchi is valued for its hemostatic and microcirculatory effects—making it especially beneficial for maintaining healthy capillary function and reducing stress on glomerular structures. Its active compounds, known as notoginsenosides, have been studied for their ability to support kidney filtration, reduce protein leakage, and enhance antioxidant defenses. This 4:1 extract delivers concentrated botanical support for kidney health, cardiovascular resilience, and tissue repair.
Rehmannia
(Rehmannia glutinosa) Root Extract 4:1
Rehmannia is a foundational herb in traditional Chinese medicine, known for its ability to nourish kidney vitality and soothe inflammation†. Often called the “kidney tonic” of Eastern herbalism, Rehmannia supports healthy kidney structure by helping to regulate fibrotic pathways and reduce oxidative stress in renal tissues. Research suggests it can inhibit markers like TGF-β1 and collagen buildup—two key drivers of kidney scarring. This concentrated 4:1 extract delivers the restorative properties of Rehmannia in a form well-suited for those seeking long-term kidney and adrenal support.
Astragalus
(Astragalus membranaceus) Root Extract 10:1
Astragalus is one of the most clinically studied herbs for kidney support, traditionally used to boost vitality, immune function, and healthy filtration†. In both traditional Chinese medicine and modern nephrology, Astragalus has earned a reputation for helping reduce proteinuria, support glomerular filtration rate (GFR), and protect kidney tissue from inflammation and oxidative stress. Its polysaccharides and saponins work at the cellular level to modulate immune responses and improve microcirculation. This 10:1 extract provides a potent dose of Astragalus’ core benefits, making it a cornerstone herb for early-stage kidney and immune resilience.
Dan Shen
(Salvia miltiorrhiza) Root Extract 10:1
Dan Shen is a traditional cardiovascular and kidney-support herb known for promoting healthy blood flow and protecting tissues from oxidative stress†. Often used to support renal microcirculation, Dan Shen helps maintain healthy filtration by improving blood flow through delicate capillary networks in the kidneys. Its active compounds—tanshinones and salvianolic acids—are powerful antioxidants shown to reduce proteinuria, ease inflammation, and support vascular integrity. This concentrated 10:1 extract is ideal for those seeking botanical support for kidney, heart, and endothelial function—all in one.
Organic Cordyceps
Fruiting Body/Mushroom Extract 10:1
Cordyceps is a revered medicinal mushroom traditionally used to support kidney vitality, energy levels, and immune resilience†. Rich in adenosine, cordycepin, and polysaccharides, Cordyceps enhances cellular energy (ATP) production and protects against oxidative damage, especially in the kidneys, lungs, and adrenal glands. Studies suggest Cordyceps may help improve serum creatinine and reduce inflammation in early-stage kidney concerns. This 10:1 fruiting body extract delivers concentrated adaptogenic support for stamina, detoxification, and overall renal balance.
Schisandra
Fruit Extract 4:1
Schisandra is an adaptogenic berry used to support stress resilience, kidney and liver function, and antioxidant defenses†. Rich in lignans like schisandrin, this powerful fruit helps protect kidney and liver cells from oxidative stress while supporting healthy cortisol and nitric oxide levels. Traditionally known to “preserve essence” in Chinese medicine, Schisandra supports fluid balance, stamina, and healthy detoxification pathways. This 4:1 extract offers a concentrated dose of its protective and balancing effects—ideal for those managing long-term stress, inflammation, or fatigue related to kidney health.
Ginger
Root Extract 4:1
Ginger Root is a warming botanical known for its anti-inflammatory, digestive, and kidney-supportive properties†. Long used in herbal traditions to soothe the gut and stimulate circulation, ginger also plays a powerful role in protecting the kidneys from oxidative stress. Studies show it can help reduce creatinine levels, lower blood sugar, and mitigate inflammation in diabetic and toxic kidney models. Its active compounds, like gingerols and shogaols, support metabolic balance and immune modulation—making this 4:1 extract a valuable addition to both kidney and whole-body wellness routines.
Serving Size: 2 capsule; Servings Per Container: 60
- Amount Per Serving % DV
- Fo-Ti (Polygonum multiflorum) Root Extract 4:1 375mg *
- Tienchi Ginseng (Panax notoginseng) Root Extract 4:1 250mg *
- Rehmannia (Rehmannia glutinosa) Root Extract 4:1 250mg *
- Astragalus (Astragalus membranaceus) Root Extract 10:1 150mg *
- Dan Shen (Salvia miltiorrhiza) Root Extract 10:1 125mg *
- Organic Cordyceps (Cordyceps sinensis) Fruiting Body/Mushroom Extract 10:1 120g *
- Schisandra Fruit Extract 4:1 120g *
- Ginger Root Extract 4:1 30mg *
*Daily value (DV) not established. Other ingredients: Hypromellose (Veggie Capsule), Magnesium Stearate, Rice Flour.
Take 2 capsules twice daily with food, or as directed by your healthcare professional.†
KYGENESIS® Kidney Prime® is your daily foundation for long-term kidney wellness.
This powerful blend of antioxidant-rich herbs, anti-inflammatory compounds, and targeted nutrients helps protect kidney tissue, promote natural detoxification, and maintain healthy filtration function.†
Kidney Prime® supports the body’s natural defense systems, balances stress responses, and encourages optimal kidney performance—making it an ideal first step in your kidney health regimen.†
KYGENESIS® ensures only the highest-quality ingredients go into every capsule. With strict third-party testing and expert-formulated blends, Kidney Prime® reflects our commitment to clean, effective, and kidney-friendly supplementation.†
Store in a cool, dry place. Consult your health care professional before use if you are pregnant or nursing, have or had a medical condition, or are taking any medication. Do not use if seal is broken or missing.
Keep out of reach of children.
How KYGENESIS® Kidney Prime®
Compares to other supplements
Most “kidney” supplements only offer general support—or use under-dosed herbs without clinical backing. KYGENESIS® Kidney Prime® is different: it’s a foundational formula designed by naturopaths to target kidney filtration, oxidative stress, and inflammation. A potent, daily defense built for long-term resilience.†
Common questions: About KYGENESIS® Kidney Prime®
This is your foundational daily support. See how others are using it to protect filtration, reduce creatinine, and feel stronger every day.
What makes KYGENESIS® different from other kidney supplements?
Kidney Prime® is a foundational formula designed by naturopaths to provide daily support for kidney resilience. It combines traditional herbs, adaptogens, and antioxidant-rich nutrients that specifically target filtration stress, inflammation, and early signs of kidney imbalance.†
Who is this formula best suited for?
It’s ideal for anyone looking to proactively support kidney function—whether you’re managing early-stage kidney concerns, addressing risk factors like high blood pressure or blood sugar, or simply maintaining long-term kidney health.†
How do I take it for best results?
Take 2 capsules twice daily with food, or as directed by your healthcare professional.†
Is it safe to use long-term?
Yes, the ingredients in this formula are clinically studied and traditionally used for ongoing kidney and metabolic support.†
Can I take it with other supplements or medications?
In most cases, yes, but check with your healthcare provider. This formula includes potent botanicals that are generally well-tolerated but should be reviewed for potential interactions.†
What should I pair this with for deeper support?
Kidney Prime® pairs well with KYGENESIS® Kidney Advance®, Nanna’s Kidney Tea, or the Alkalizing Formula. Each targets a different aspect of kidney wellness, making them great additions to a full support plan.†
What do extract ratios like 10:1 or 4:1 mean, and how much herb am I getting?
Extract ratios tell you how much raw plant material was used to produce the final, concentrated extract. The higher the ratio, the more concentrated the extract.
A 10:1 extract means 10 parts of raw herb were used to make 1 part of extract. So if your supplement contains 100 mg of a 10:1 extract, it’s equivalent to 1,000 mg (1 gram) of the whole herb.
A 4:1 extract means 4 parts of raw herb become 1 part of extract. So if your supplement contains 100 mg of a 4:1 extract, that equals 400 mg of the raw herb.
These concentrated extracts allow you to get the full benefit of therapeutic doses, without needing to take large quantities. They also ensure better consistency, quality, and potency from capsule to capsule.
Complete KYGENESIS® Routine

Kidney Advance®
Foundational antioxidant support to reduce oxidative stress and support kidney function.
- Serving Size: 1 Capsule
- Serving Per Container: 60 Capsules
- 30-day supply

Gluco Restore™
Supporting healthy blood sugar and reducing diabetic stress on kidneys.
- Serving Size: 1 Capsule
- Serving Per Container: 90 Capsules
- 30-day supply

Cardio Restore™
Supporting healthy blood pressure and cardiovascular health linked to kidney function.
- Serving Size: 2 Capsule
- Serving Per Container: 120 Capsules
- 30-day supply
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