“My GFR went from stage 3 to 69—and I feel better at 77 than I have in years, thanks to Kidney Coach.”





Kidney Support Protocol
Daily foundational support for kidney function. Combines KYGENESIS® Kidney Prime® and KYGENESIS® Kidney Advance® for antioxidant protection, filtration support, and natural defense against kidney decline.†
Can I cancel my subscription anytime?
Yes—absolutely. You’re in full control. You can cancel your subscription at any time, but please make sure to do so at least 3 days before your next scheduled payment to avoid being charged for the upcoming month. This gives our team enough time to process the request smoothly. If you need help, our support team is always here to assist.
Benefits of KYGENESIS® Kidney Support Protocol
- Strengthen Daily Kidney Function
Combines foundational herbal support with antioxidant protection to help your kidneys filter waste more effectively—day in and day out.†
- Lower Creatinine & Improve eGFR
Supports measurable improvement in bloodwork through targeted herbal formulas backed by clinical research.†
- Protect Against Kidney Decline
Designed to slow down the root causes of kidney deterioration including inflammation, oxidative stress, and poor circulation.†
- Support Blood Flow & Nutrient Delivery
Improves microcirculation to your kidneys, enhancing their ability to heal and function naturally.†
- Enhance Immune & Detox Response
Herbs like astragalus and cordyceps help your body mount a stronger defense and eliminate waste more efficiently.†
- Ease Day-to-Day Discomforts
Can help relieve bloating, fluid retention, and other subtle kidney-related symptoms over time.†
- Empower Your Kidney Health Routine
Take the guesswork out of natural kidney care with a simple, proven bundle used by thousands globally.†
When it comes to daily kidney care, consistency is everything. This bundle provides a strong foundation for kidney wellness—supporting natural filtration, reducing inflammation, and promoting long-term function with simplicity and confidence.†
Suggested Use
Take 2 capsules of KYGENESIS® Kidney Prime® twice daily, preferably with breakfast or lunch.Take 1 capsule of KYGENESIS® Kidney Advance® twice daily, with meals (e.g., breakfast and dinner).
Science-Based Formula
Made in the USA with domestic and imported ingredients.
Manufactured in a GMP-Certified Facility
Formulated with Non-GMO Ingredients
100% Vegan-Friendly
Manufactured in an FDA-Registered Facility
Antioxidant
Kidneys
Blood Sugar†
Cardio Health†
Immunity†
Anti-Aging†
Energy†
Cellular Energy†
What’s inside matters:
Foundational kidney support, simplified.
This essential bundle pairs KYGENESIS® Kidney Prime® and Kidney Advance®—delivering a powerful one-two punch of foundational vitamins, minerals, and targeted herbs. Together, they help reduce oxidative stress, ease inflammation, and strengthen filtration function, making this bundle ideal for daily kidney maintenance and protection.†
R-Alpha Lipoic Acid
(R-ALA)
R-Alpha Lipoic Acid is a potent antioxidant that helps protect kidney cells from oxidative stress and supports healthy energy production†. It plays a key role in mitochondrial function, helping the body convert nutrients into cellular energy while neutralizing free radicals that can damage kidney tissue. This bioavailable form is the naturally occurring isomer most effectively used by the body. In those with blood sugar concerns or early kidney dysfunction, R-Alpha Lipoic Acid supports nerve health, glucose metabolism, and vascular function—all critical for long-term kidney resilience. Often used in clinical protocols for its ability to stabilize oxidative markers and protect renal endothelial health.
N-Acetyl-L-Cysteine
(NAC)
N-Acetyl-L-Cysteine (NAC) is a powerful antioxidant precursor that supports kidney detoxification, cellular repair, and respiratory health†. As a direct precursor to glutathione—your body’s master antioxidant—NAC helps replenish cellular defenses and protect kidney tissue from oxidative and inflammatory stress. It has been studied for its role in maintaining healthy creatinine levels, especially during times of acute kidney strain or exposure to environmental toxins. NAC also supports immune function and lung health, making it a favorite in both nephrology and integrative medicine for comprehensive detox and cellular resilience.
Ubiquinol
(Active CoQ10)
Ubiquinol is the active, bioavailable form of CoQ10 that supports cellular energy production and helps protect kidney and heart tissues from oxidative damage†. Found naturally in every cell, especially in high-energy organs like the kidneys and heart, Ubiquinol fuels mitochondria and enhances resilience against stress and aging. As we get older—or in states of chronic inflammation—our ability to convert CoQ10 into its active form declines. Ubiquinol supplementation helps restore this balance, supporting circulation, blood pressure regulation, and energy metabolism in ways that benefit both cardiovascular and kidney health.
BioPerine®
Black Pepper Fruit Extract
BioPerine® is a standardized black pepper fruit extract that enhances nutrient absorption and supports metabolic efficiency†. Clinically shown to increase the bioavailability of key nutrients—including CoQ10, curcumin, and herbal compounds—BioPerine® helps ensure your body fully utilizes the ingredients in each formula. It also supports digestive health, antioxidant activity, and healthy circulation. By boosting the effectiveness of other nutrients, BioPerine® plays a quiet but critical role in optimizing kidney and systemic wellness protocols.
Fo-Ti
(Polygonum multiflorum) Root Extract 4:1
Fo-Ti is a revered root in traditional Chinese medicine known for its restorative properties and support of kidney, liver, and longevity systems†. Often used to “nourish the kidneys” and support healthy aging, Fo-Ti contains antioxidant compounds like stilbene glycosides that help defend against cellular damage and oxidative stress. Modern research suggests Fo-Ti may help protect renal function by supporting healthy mitochondrial activity and reducing markers of fibrosis. This 4:1 extract offers a concentrated form of its rejuvenating benefits—ideal for those seeking foundational kidney and vitality support.
Tienchi Ginseng
(Panax notoginseng) Root Extract 4:1
Tienchi Ginseng is a prized adaptogenic root traditionally used to support circulation, reduce inflammation, and protect delicate vascular networks like those in the kidneys†. Unlike common ginsengs, Tienchi is valued for its hemostatic and microcirculatory effects—making it especially beneficial for maintaining healthy capillary function and reducing stress on glomerular structures. Its active compounds, known as notoginsenosides, have been studied for their ability to support kidney filtration, reduce protein leakage, and enhance antioxidant defenses. This 4:1 extract delivers concentrated botanical support for kidney health, cardiovascular resilience, and tissue repair.
Rehmannia
(Rehmannia glutinosa) Root Extract 4:1
Rehmannia is a foundational herb in traditional Chinese medicine, known for its ability to nourish kidney vitality and soothe inflammation†. Often called the “kidney tonic” of Eastern herbalism, Rehmannia supports healthy kidney structure by helping to regulate fibrotic pathways and reduce oxidative stress in renal tissues. Research suggests it can inhibit markers like TGF-β1 and collagen buildup—two key drivers of kidney scarring. This concentrated 4:1 extract delivers the restorative properties of Rehmannia in a form well-suited for those seeking long-term kidney and adrenal support.
Astragalus
(Astragalus membranaceus) Root Extract 10:1
Astragalus is one of the most clinically studied herbs for kidney support, traditionally used to boost vitality, immune function, and healthy filtration†. In both traditional Chinese medicine and modern nephrology, Astragalus has earned a reputation for helping reduce proteinuria, support glomerular filtration rate (GFR), and protect kidney tissue from inflammation and oxidative stress. Its polysaccharides and saponins work at the cellular level to modulate immune responses and improve microcirculation. This 10:1 extract provides a potent dose of Astragalus’ core benefits, making it a cornerstone herb for early-stage kidney and immune resilience.
Dan Shen
(Salvia miltiorrhiza) Root Extract 10:1
Dan Shen is a traditional cardiovascular and kidney-support herb known for promoting healthy blood flow and protecting tissues from oxidative stress†. Often used to support renal microcirculation, Dan Shen helps maintain healthy filtration by improving blood flow through delicate capillary networks in the kidneys. Its active compounds—tanshinones and salvianolic acids—are powerful antioxidants shown to reduce proteinuria, ease inflammation, and support vascular integrity. This concentrated 10:1 extract is ideal for those seeking botanical support for kidney, heart, and endothelial function—all in one.
Organic Cordyceps
Fruiting Body/Mushroom Extract 10:1
Cordyceps is a revered medicinal mushroom traditionally used to support kidney vitality, energy levels, and immune resilience†. Rich in adenosine, cordycepin, and polysaccharides, Cordyceps enhances cellular energy (ATP) production and protects against oxidative damage, especially in the kidneys, lungs, and adrenal glands. Studies suggest Cordyceps may help improve serum creatinine and reduce inflammation in early-stage kidney concerns. This 10:1 fruiting body extract delivers concentrated adaptogenic support for stamina, detoxification, and overall renal balance.
Schisandra
Fruit Extract 4:1
Schisandra is an adaptogenic berry used to support stress resilience, kidney and liver function, and antioxidant defenses†. Rich in lignans like schisandrin, this powerful fruit helps protect kidney and liver cells from oxidative stress while supporting healthy cortisol and nitric oxide levels. Traditionally known to “preserve essence” in Chinese medicine, Schisandra supports fluid balance, stamina, and healthy detoxification pathways. This 4:1 extract offers a concentrated dose of its protective and balancing effects—ideal for those managing long-term stress, inflammation, or fatigue related to kidney health.
Ginger
Root Extract 4:1
Ginger Root is a warming botanical known for its anti-inflammatory, digestive, and kidney-supportive properties†. Long used in herbal traditions to soothe the gut and stimulate circulation, ginger also plays a powerful role in protecting the kidneys from oxidative stress. Studies show it can help reduce creatinine levels, lower blood sugar, and mitigate inflammation in diabetic and toxic kidney models. Its active compounds, like gingerols and shogaols, support metabolic balance and immune modulation—making this 4:1 extract a valuable addition to both kidney and whole-body wellness routines.

KYGENESIS®
Kidney Advance®
Deep kidney defense from within delivers powerful internal support for long-term kidney resilience. Its concentrated blend of botanicals, adaptogens, and antioxidant-rich herbs helps to ease inflammatory load, improve filtration efficiency, and strengthen your body’s natural detox processes—making it an ideal ally in multi-supplement kidney support protocols.†
200mg
R-Alpha Lipoic Acid is a potent antioxidant that protects kidney function, improves glucose metabolism, and supports healthy energy production, and cardiovascular function.†
150mg
Ubiquinol (Active CoQ10) supports mitochondrial energy production; promotes heart and kidney health; protects cells from oxidative stress; aids in maintaining healthy blood pressure.†
200mg
N-Acetyl-L-Cysteine which helps to protect kidney function; supports healthy immune function and blood pressure; helps prevent oxidative damage of kidney cells and helps kidney detoxification.†
5mg
BioPerine® Black Pepper Fruit Extract Enhances absorption and bioavailability of antioxidants and other nutrients.

KYGENESIS®
Kidney Prime®
Foundational kidney strength for everyday health combines clinically studied botanicals and supportive nutrients to help fortify kidney health at the root. Its daily use supports filtration, encourages natural repair pathways, and defends against oxidative stress—making it a core companion in any kidney wellness protocol.†
375mg
Fo-Ti (Polygonum multiflorum) is traditionally used in Chinese medicine to support kidney and liver health, Fo-Ti helps promote longevity, reduce oxidative stress, and nourish the adrenal and endocrine systems—key to maintaining energy and kidney resilience.†
250mg
Rehmannia (Rehmannia glutinosa) is a traditional herb used in Eastern medicine to nourish the kidneys, cool inflammation, and support adrenal health. Known for its restorative properties, it may help protect kidney tissues, improve circulation, and promote vitality in those with chronic kidney challenges.†
125mg
Dan Shen (Salvia miltiorrhiza) is a revered herb in Traditional Chinese Medicine known for promoting healthy blood flow and reducing inflammation. It supports microcirculation within the kidneys, protects against oxidative damage, and may help maintain optimal filtration function over time.†
120mg
Schisandra Fruit is a powerful adaptogenic berry traditionally used to support stress resilience, liver and kidney function, and overall vitality. Rich in lignans and antioxidants, it helps reduce inflammation, enhance detoxification pathways, and protect kidney tissues from oxidative damage.†
250mg
Tienchi Ginseng (Panax notoginseng) is a prized adaptogen known to support healthy circulation, reduce inflammation, and strengthen capillaries. Often used to protect kidney microvasculature and promote natural healing at the cellular level.†
150mg
Astragalus (Astragalus membranaceus) is a powerful adaptogenic herb used for centuries to support kidney health, immune resilience, and vitality. It helps reduce proteinuria, modulate inflammation, and enhance the kidney’s natural repair processes—making it a cornerstone herb in traditional and modern kidney protocols.†
120mg
Organic Cordyceps (Cordyceps sinensis) Fruiting Body/Mushroom is a revered medicinal mushroom known for boosting energy, oxygen utilization, and kidney vitality. It supports renal function by enhancing mitochondrial activity, reducing inflammation, and protecting against damage caused by oxidative stress and toxins.†
30mg
Ginger Root is a well-known botanical with potent anti-inflammatory and antioxidant properties. It supports healthy digestion, promotes circulation, and helps reduce inflammation that can contribute to kidney stress. Ginger also aids in metabolic balance and supports overall detoxification.†
Trusted by 51K+
people worldwide
Hear directly from people who reversed their kidney decline.
“My GFR rose from 28 to 37, and my creatinine dropped - this program helped me take back control.”
Matt
“My eGFR improved from 49 to 58, my doctor was stunned. This program gave me tools to actually heal.”
Marty
“My GFR rose from 27 to 38 and my creatinine dropped—this lifestyle and supplement change saved my kidneys.”
Vern
“My GFR rose from 27 to 38 and my creatinine dropped—this lifestyle and supplement change saved my kidneys.”
Jan
“From fear and fatigue to stage 2 recovery. Program helped restore my GFR and my trust in my body.”
Paul
“My GFR rose from 15 to 27—and I feel healthier, clearer, and more energized than I have in decades.”
Linda
“My GFR jumped from 55 to 75, and my creatinine dropped—all from following the Kidney Coach protocol.”
Richard
Common questions: About KYGENESIS® Kidney Support Protocol
Looking for a simple, foundational approach? This FAQ covers why combining Prime® and Advance® is the daily duo many rely on.†
What’s the goal of combining these two supplements?
Together, they provide foundational kidney protection—supporting healthy filtration, reducing oxidative stress, and reinforcing overall kidney resilience.†
Do I take both at the same time?
You can, or space them throughout the day. Just make sure to take them with food for optimal absorption.†
Can I use this bundle long-term?
Yes, it’s designed for daily, ongoing support. Many people use this combo as part of their maintenance routine.†
Will this help improve my creatinine or GFR?
Many users have seen improvements in lab markers with consistent use—especially when paired with Kidney Coach lifestyle strategies.†
Can I take other supplements alongside this bundle?
Absolutely. These formulas are designed to be compatible with most kidney-friendly supplements. Always speak to your provider if unsure.†
What stage of kidney disease is this best for?
This protocol is ideal for anyone in early to mid-stages or those wanting to maintain function post-transplant or post-recovery.†
Complete KYGENESIS® Routine

Kidney Support Protocol
Reclaim Function. Protect What Matters.
- Included in Bundle:
KYGENESIS® Kidney Prime®
KYGENESIS® Kidney Advance®
- 30-day supply

Kidney Essential Protocol
Core support for daily health.
- Included in Bundle:
KYGENESIS® Kidney Prime®
KYGENESIS® Kidney Advance®
KYGENESIS® Nanna’s Kidney Tea - 30-day supply

Cardio Restore™
Supporting healthy blood pressure and cardiovascular health linked to kidney function.
- Serving Size: 2 Capsule
- Serving Per Container: 120 Capsules
- 30-day supply

Kidney + Cardio Protocol
Support for kidney health, cardiovascular function.
- Included in Bundle:
KYGENESIS® Kidney Prime®
KYGENESIS® Kidney Advance®
KYGENESIS® CardioRestore™ - 30-day supply

Gluco Restore™
Supporting healthy blood sugar and reducing diabetic stress on kidneys.
- Serving Size: 1 Capsule
- Serving Per Container: 90 Capsules
- 30-day supply

Kidney + Metabolic Protocol
Kidney health and blood sugar regulation.
- Included in Bundle:
KYGENESIS® Kidney Prime®
KYGENESIS® Kidney Advance®
KYGENESIS® GlucoRestore™ - 30-day supply

Kidney Advance®
Foundational antioxidant support to reduce oxidative stress and support kidney function.
- Serving Size: 1 Capsule
- Serving Per Container: 60 Capsules
- 30-day supply

Kidney Alkalizing Formula Stages 1-3
Balancing pH, reducing acidosis, and supporting kidney health at any stage.
- Serving Size: 1 Scoop
- Serving Per Container: 30 servings
- 30-day supply

Kidney Alkalizing Formula Stages 4-5
Balancing pH, reducing acidosis, and supporting kidney health at any stage.
- Serving Size: 1 Scoop
- Serving Per Container: 30 servings
- 30-day supply

Kidney Prime®
Herbal kidney protection - blood flow, inflammation, and kidney tissue support.
- Serving Size: 2 Capsules
- Serving Per Container: 120 Capsules
- 30-day supply

Kidney Repair Protocol 1-3
For kidney function, inflammation, and alkalinity
- Included in Bundle:
KYGENESIS® Kidney Prime®
KYGENESIS® Kidney Advance®
KYGENESIS® Kidney Alkalizing Formula - 30-day supply

Kidney Repair Protocol 4-5
For kidney function, inflammation, and alkalinity
- Included in Bundle:
KYGENESIS® Kidney Prime®
KYGENESIS® Kidney Advance®
KYGENESIS® Kidney Alkalizing Formula - 30-day supply

Nanna’s Kidney Tea
Gentle kidney support, urinary tract health, and stress relief.
- Serving Size: 1 tea bag
- Serving Per Container: 60 servings
- 30-day supply
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Advanced Kidney DefenseKidney Repair Protocol 4-5
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Core Kidney DetoxKidney Essential Protocol
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Daily Foundational SupportKidney Support Protocol
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Herbal NourishmentNanna’s Kidney Tea
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Heart SupportCardio Restore™
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Cellular SupportKidney Prime®
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Filtration ProtectionKidney Advance®
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Acid BufferingKidney Alkalizing Formula Stages 4-5
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