New Bundle Pack

Kygenesis Kidney Support Protocol Essentials


  • Supports healthy kidney & urinary tract function†
  • Promotes normal creatinine & urea levels†
  • Protects kidney cells and tissues†
  • Increases cellular energy & promotes a calm mood†
  • Activates anti-aging genes†

Original price was: $185.00.Current price is: $172.00. or Original price was: $185.00.Current price is: $137.60. / month

(Price in USD)

Subscription Discount Chart - Up to 30% Off!

Month Price
1 - 2 $172.00
3 - 4 $129.00
5+ $120.40
Next Day Shipping

Next Day Shipping
orders ship within 24 hrs

Savings on all Bulk Orders

Up to 30% Savings
on all Subscriptions

Made In the USA

Made In the USA

GMP Certified

GMP Certified Facility

Science-Based Formula

Science-Based Formulas

Why Kygenesis Kidney Support Protocol

Formulated by Kygenesis Naturopaths based on decades of research and clinical practice, the Kidney Support Protocol includes two synergistic supplements and a kidney-specific herbal tea:

Kidney Advance®, Kidney Prime® + Kidney Tea

A potent combination of specialized antioxidants, micronutrients, and phytonutrients, the ingredients in Kygenesis supplements and tea are clinically proven to minimize the damage of stress and promote the body’s own healing powers as we age.

Together with a healthy lifestyle, Kygenesis protects kidney tissues, promotes kidney and urinary tract health, supports cardiovascular and blood sugar function — and more.

Read the Active Ingredients to learn how each evidence-based ingredient defends against the effects of aging.

Kidney Support Protocol Active Ingredients

Kidney Advance® Formula

This concentrated nutritional formula includes a combination of micronutrients clinically proven to support kidney health and vitality at the cellular level.

R-Alpha Lipoic Acid (200 mg): A potent antioxidant that protects kidney function, improves glucose metabolism, supports healthy energy production, and cardiovascular function.

Lipoic Acid

Coenzyme Q10 (150 mg): Reduces creatinine and urea; supports cardiovascular health; reduces free radical damage, and promotes natural energy.

N-Acetyl-L-Cysteine (200 mg): Helps to protect kidney function; supports healthy immune function and blood pressure; helps prevent oxidative damage of kidney cells and helps kidney detoxification.

N-Acetyl Cysteine

BioPerine® Black Pepper Extract (95% Piperine, 5 mg): Enhances absorption and bioavailability of antioxidants and other nutrients.

Kidney Prime® Formula

Rich in phytonutrients, adaptogens, and bio-modulators, the ingredients in Kidney Prime™ are clinically-proven to help protect the kidney tissues from damage and reduce the biomarkers of CKD (e.g. creatinine and urea).

Because Kygenesis uses highly-concentrated extracts, you get a formula with 4X to 10X more potency. New in late 2021, Kidney Prime is even more concentrated, with 6x more Dan Shen, and up to 150% more of other key herbal ingredients.

Dan Shen root extract 10:1 (250 mg):— NOW 6X MORE POTENT

Protects and supports kidney function; promotes healthy blood pressure; helps to normalize blood glucose levels, improve circulation, prevent oxidative damage, and reduce scarring of the kidneys.

Dan Shen

Astragalus root extract 10:1 (300 mg)*: Supports normal glucose and creatinine levels; protects kidney cells from damage, promotes healthy energy production, and supports healthy immune function.

Rehmannia root extract 4:1 (500 mg)**:—   NOW 70% MORE POTENT

Protects the kidney cells from damage; helps to reduce scarring and deposits in the kidneys; supports the reduction of protein and blood in the urine; increases blood flow and oxygen to the kidneys, and helps to protect against diabetes.


Tienchi Ginseng root extract 4:1 (500 mg)**:— NOW 70% MORE POTENT

Protects the kidney tissues from damage; supports normal blood sugar and cholesterol levels and promotes cardiovascular health.

Fo-Ti root extract 4:1 (750 mg)**:— NOW 150% MORE POTENT

Helps to protect the kidney tissues through anti-oxidant and anti-inflammatory actions; increases Klotho expression; promotes normal cholesterol levels; supports cardiovascular health, energy production, cognitive health, and more.


Cordyceps mushroom extract 10:1 (240 mg)*: Helps reduce the biomarkers of CKD, including creatinine and blood urea nitrogen; protects kidney cells from damage and the effects of hypertension; improves Klotho expression.

Schisandra fruit extract 10:1 (240 mg)*: Helps to protect against kidney cell damage through anti-oxidant and anti-inflammatory actions; supports healthy blood glucose and triglyceride levels; promotes normal blood pressure levels.


Ginger root extract 4:1 (60 mg)**: Enhances absorption of other ingredients; helps increase blood flow to the kidneys.

*100 mg of extract is equivalent to 1000 mg of pure herb.
**100 mg of extract is equivalent to 400 mg of pure herb.

Why Increasing Klotho Matters for Kidneys

Klotho was initially identified as a longevity gene, but further research has shown that it’s much more than that.

The Klotho gene produces an enzyme that’s key for kidney health, normal blood pressure, blood glucose, bone density, and more.

With age and when the kidneys are stressed or damaged, Klotho levels decline — which means, your kidneys don’t get the protective benefits of high Klotho levels.

Research shows that raising Klotho levels exerts a protective effect on the kidney cells and tissues and other vital organs.

That’s why Kygenesis Kidney Prime® includes both Fo-Ti and Cordyceps, ingredients that increase Klotho levels naturally.

Kidney Tea Formula®

Kidney Tea is our special blend of raw and organic herbs traditionally used to support kidney health for centuries.

Mild tasting, slightly sweet and earthy, Kidney Tea eases stress while purifying, soothing, and protecting the vital systems connected to kidney health.


Nettle leaf (organic): Dense in nutrients and antioxidants, nettle leaf (also known as stinging nettle) has long been a staple of herbal traditions. The leaf is widely accepted as a support for the kidneys and urinary system. It also promotes cardiovascular health and normal blood sugar.

Lavender (organic): Beloved for its proven calming effects, delicate flavor, and aroma. Lavender helps to reduce stress that can take a toll on kidney health. It promotes a deeper sleep, healthy blood pressure, and eases digestive discomfort.

Couch grass: Sweet-tasting couch grass root is best known as a natural diuretic and purifier to support clear and healthy kidneys. It also promotes a healthy urinary tract, blood pressure and liver function. 

Marshmallow root (organic): Used in herbal medicine for centuries, marshmallow root is a high antioxidant demulcent that soothes the urinary system, promotes a healthy urinary tract, and flushes out excess fluid while purifying.

Kygenesis is the protocol our Naturopaths recommend in their clinics

For decades, the Kygenesis Naturopaths have been recommending the ingredients in Kidney AdvanceTM, Kidney PrimeTM and Kidney TeaTM.

We know these are the ingredients that get the best results — based on evidence from decades of clinical experience, medical research, and thousands of years of traditional herbal therapeutics.

Until we created Kygenesis, patients had to seek out these ingredients separately. Nothing else with this combination of kidney-specific nutritional and herbal support exists in a pure and concentrated formula.

That’s why our team of Naturopaths created Kygenesis.



Cardio Health

Blood Sugar

Cellular Energy

Anti Aging


“Now back in the normal range”

“With the help of the supplements, my creatinine level went from 1.29 to 1.20 in about 4 months.
My creatinine level is now back in the normal range as listed by the lab which reported the results. (0.61—1.24).”

Michael Collins

“Within a month GFR was 44”

“I bought the supplements recommended and have been taking them for 4 months now.
My GFR on Feb 2 was 27, creatinine 2.25 and bun 60. Within a month GFR was 44, creatinine 1.5, Bun 42. The last blood test on 13 May GFR 44 creatinine 1.5 bun 35.”

Wayne Olson


Pure and potent. Kygenesis sources ingredients only from the highest-quality growers and producers. Each batch is tested for purity. And because we use potent extracts, you get a supplement that’s up to 10X more powerful in a smaller dose.


From our clinics to you. Kygenesis was formulated by a team of Naturopaths who specialize in treating kidney disease. These are the exact supplements we prescribe to our patients.


Every ingredient in Kygenesis is backed by clinical evidence demonstrating that these nutrients and herbs improve kidney health. It’s the ideal protocol for anyone whose kidneys need support.

Kygenesis Kidney Support Protocol

Kidney Advance®+ Kidney Prime® Bundle + Kidney Tea Bundle

Next Day Shipping

Next Day Shipping
orders ship within 24 hrs

Savings on all Bulk Orders

Up to 30% Savings
on all Subscriptions

Kidney Support Protocol Suggested Use

Kygenesis Kidney Advance®, Kidney Prime®, and Kidney Tea are complementary supplements. Take both daily for optimal results. Each kit contains a one-month supply.

Kidney Advance®: Take 1 capsule two times daily (or as directed by your qualified healthcare professional). Continue daily use for ongoing kidney support.

Kidney Tea: Drink one to two cups a day. If your doctor has given you a ‘fluid allowance,’ please make sure you include this tea as part of that allowance.

Kidney Prime®: Take 2 capsules two times daily (or as directed by your qualified healthcare professional). Continue daily use for ongoing kidney support.

Kygenesis Naturopaths recommend taking Kidney Advance® and Kidney Prime® in the morning and evening, with meals.

Kidney Support Protocol FAQs

Kygenesis formulas are developed by Naturopaths with deep clinical and research experience in kidney health. The ingredients are pure, premium and many are concentrated extracts for up to 10X more potency.

Each individual responds differently to the supplements in Kygenesis.

Before taking Kygenesis, be sure you have the results from blood work. Repeat the blood tests after 3-4 months of consistently taking Kygenesis daily.

We also recommend keeping a daily symptom diary. A sense of wellbeing, improved energy and mental clarity are often the first noticeable improvements.

Kygenesis supplements are most effective when combined with a diet that promotes kidney health, exercise and meditation or other practices that reduce stress.

Kygenesis is made from ingredients that are deemed safe for the general population when taken as recommended. If you have a pre-existing health condition, are pregnant or lactating, consult a healthcare professional before using any nutritional supplement.

Some pharmaceuticals cannot be taken with specific nutritional supplements. If you are taking any medication we recommend speaking to your professional health care provider or emailing customer support at [email protected].

Kygenesis is formulated to support kidney function but cannot recommend that you substitute these supplements for prescribed medication or recommended over-the-counter medication. Please consult with your qualified health-care practitioner for advice on your medication.

The nutrients and herbs in Kygenesis support kidneys under stress. Over time, with age and accumulated stress on our organs, normal kidney function can be increasingly challenged. Your kidneys work hard every day. Kygenesis is formulated to deliver the daily support that helps maintain normal function.

Kygenesis supplements are calibrated for maximum efficacy and safety at the recommended dose — not above. Please follow the dosage guidelines or as directed by your healthcare professional.

Domestic US and international shipping costs vary depending on the shipping method you choose at checkout. You will see the shipping costs in your checkout process and can adjust your shipping method before placing your order.

Kygenesis is prepared in New York, in a multi-award-winning FDA registered facility, certified GMP by NSF International through independent audits. The chemists and technicians operate to the highest standards of quality.

Kygenesis Kidney Tea is blended in Australia to the highest quality standards.

Please email our Customer Service at [email protected]

Our original Kidney Prime formula has always been more concentrated than other supplements because we use herbal extracts. To deliver even more potent, effective support for your kidneys, we have increased the concentration of all but one herb. The new formula contains 6x more Dan Shen, and 70% to 150% more of several key ingredients.

If you’ve been taking the Kidney Prime original formula, we think you’ll be excited to know that the new formula available now is more potent. This updated formula contains 6x more Dan Shen, and 70% to 150% more of several key ingredients. 

You’ll now get this enhanced formula for the same price, and we’re adding an additional 30 capsules to the bottle as we want you to take four per day, for best results. Simply space out your intake as you did with the original formula. Your Kidney Prime bottle will last a month.

Kygenesis Kidney Support Protocol

Kidney Advance® + Kidney Prime® Bundle + Kidney Tea Bundle

Next Day Shipping

Next Day Shipping
orders ship within 24 hrs

Savings on all Bulk Orders

Up to 30% Savings
on all Subscriptions