Kygenesis Kidney Support Protocol (Copy)


  • Supports healthy kidney function†
  • Promotes normal creatinine & urea levels†
  • Protects kidney cells and tissues†
  • Increases cellular energy†
  • Activates anti-aging genes†

Original price was: $146.00.Current price is: $138.70. or Original price was: $146.00.Current price is: $110.96. / month

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1 - 2 $138.70
3 - 4 $104.02
5+ $97.09
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Made In the USA

Made In the USA

GMP Certified

GMP Certified Facility

Science-Based Formula

Science-Based Formulas

Why Kygenesis Kidney Support Protocol

Formulated by Kygenesis Naturopaths based on decades of research and clinical practice, the Kidney Support Protocol includes two synergistic supplements:

Kidney Advance™ and Kidney Prime™.

A potent combination of specialized antioxidants, micronutrients, and phytonutrients, these ingredients are clinically proven to minimize the damage of stress and promote the body’s own healing powers.

Together with a healthy lifestyle, Kygenesis supplements protect kidney tissues, promote kidney health, support cardiovascular and blood sugar function, while defending against the effects of aging.

Read the Active Ingredients to learn how each evidence-based ingredient supports kidney health.

Kidney Support Protocol Active Ingredients

Kidney Advance™ Formula

This concentrated nutritional formula includes a combination of micronutrients clinically proven to support kidney health and vitality at the cellular level.

R-Alpha Lipoic Acid (200 mg): A potent antioxidant that protects kidney function, improves glucose metabolism, supports healthy energy production, and cardiovascular function.

Lipoic Acid

Coenzyme Q10 (150 mg): Reduces creatinine and urea; supports cardiovascular health; reduces free radical damage, and promotes natural energy.

N-Acetyl-L-Cysteine (200 mg): Helps to protect kidney function; supports healthy immune function and blood pressure; helps prevent oxidative damage of kidney cells and helps kidney detoxification.

N-Acetyl Cysteine

BioPerine® Black Pepper Extract (95% Piperine, 5 mg): Enhances absorption and bioavailability of antioxidants and other nutrients.

Kidney Prime™ Formula

Rich in phytonutrients, adaptogens, and bio-modulators, the ingredients in Kidney Prime™ are clinically-proven to help protect the kidney tissues from damage and reduce the biomarkers of CKD (e.g. creatinine and urea).

Because Kygenesis uses highly-concentrated extracts, you get a formula with 4X to 10X more potency.

Dan Shen root (120 mg): Protects and supports kidney function; promotes healthy blood pressure; helps to normalize blood glucose levels, improve circulation, prevent oxidative damage, and reduce scarring of the kidneys.

Dan Shen

Astragalus root extract 10:1 (100 mg)*: Supports normal glucose and creatinine levels; protects kidney cells from damage, promotes healthy energy production, and supports healthy immune function.

Rehmannia root extract 4:1 (100 mg)**: Protects the kidney cells from damage; helps to reduce scarring and deposits in the kidneys; supports the reduction of protein and blood in the urine; increases blood flow and oxygen to the kidneys, and helps to protect against diabetes.


Tienchi Ginseng root extract 4:1 (100 mg)**: Protects the kidney tissues from damage; supports normal blood sugar and cholesterol levels and promotes cardiovascular health.

Fo-Ti root extract 4:1 (100 mg)**: Helps to protect the kidney tissues through anti-oxidant and anti-inflammatory actions; increases Klotho expression; promotes normal cholesterol levels; supports cardiovascular health, energy production, cognitive health, and more.


Cordyceps mushroom extract 10:1 (75 mg)*: Helps reduce the biomarkers of CKD, including creatinine and blood urea nitrogen; protects kidney cells from damage and the effects of hypertension; improves Klotho expression.

Schisandra fruit extract 10:1 (73 mg)*: Helps to protect against kidney cell damage through anti-oxidant and anti-inflammatory actions; supports healthy blood glucose and triglyceride levels; promotes normal blood pressure levels.


Ginger root extract 4:1 (20 mg)**: Enhances absorption of other ingredients; helps increase blood flow to the kidneys.

*100 mg of extract is equivalent to 1000 mg of pure herb.
**100 mg of extract is equivalent to 400 mg of pure herb.

Kidney Support Protocol Suggested Use

Kygenesis Kidney Advance™ and Kidney Prime™ are complementary supplements. Take both daily for optimal results. Each kit contains a one-month supply.

Kidney Advance™: Take 1 capsule two times daily (or as directed by your qualified healthcare professional). Continue daily use for ongoing kidney support.

Kidney Prime™: Take 1 capsule three times daily (or as directed by your qualified healthcare professional). Continue daily use for ongoing kidney support.

Kygenesis Naturopaths recommend taking Kidney Advance™ and Kidney Prime™ in the morning and evening, with meals.

Why Increasing Klotho Matters for Kidneys

Klotho was initially identified as a longevity gene, but further research has shown that it’s much more than that.

The Klotho gene produces an enzyme that’s key for kidney health, normal blood pressure, blood glucose, bone density, and more.

With age and when the kidneys are stressed or damaged, Klotho levels decline — which means, your kidneys don’t get the protective benefits of high Klotho levels.

Research shows that raising Klotho levels exerts a protective effect on the kidney cells and tissues and other vital organs.

That’s why Kygenesis Kidney Prime™ includes both Fo-Ti and Cordyceps, ingredients that increase Klotho levels naturally.

Kygenesis is the protocol our Naturopaths recommend in their clinics

For decades, the Kygenesis Naturopaths have been recommending the ingredients in Kidney AdvanceTM and Kidney PrimeTM.

We know these are the ingredients that get the best results — based on evidence from decades of clinical experience, medical research, and thousands of years of traditional herbal therapeutics.

Until we created Kygenesis, patients had to seek out these ingredients separately. Nothing else with this combination of kidney-specific nutritional and herbal support exists in a pure and concentrated formula.

That’s why our team of Naturopaths created Kygenesis.



Cardio Health

Blood Sugar

Cellular Energy

Anti Aging


“Now back in the normal range”

“With the help of the supplements, my creatinine level went from 1.29 to 1.20 in about 4 months.
My creatinine level is now back in the normal range as listed by the lab which reported the results. (0.61—1.24).”

Michael Collins

“Within a month GFR was 44”

“I bought the supplements recommended and have been taking them for 4 months now.
My GFR on Feb 2 was 27, creatinine 2.25 and bun 60. Within a month GFR was 44, creatinine 1.5, Bun 42. The last blood test on 13 May GFR 44 creatinine 1.5 bun 35.”

Wayne Olson


Pure and potent. Kygenesis sources ingredients only from the highest-quality growers and producers. Each batch is tested for purity. And because we use potent extracts, you get a supplement that’s up to 10X more powerful in a smaller dose.


From our clinics to you. Kygenesis was formulated by a team of Naturopaths who specialize in treating kidney disease. These are the exact supplements we prescribe to our patients.


Every ingredient in Kygenesis is backed by clinical evidence demonstrating that these nutrients and herbs improve kidney health. It’s the ideal protocol for anyone whose kidneys need support.

Kygenesis Kidney Support Protocol

Kidney Advance™+ Kidney Prime™ Bundle

Next Day Shipping

Next Day Shipping
orders ship within 24 hrs

Savings on all Bulk Orders

Up to 15% Savings
on all Bulk Orders

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Kidney Support Protocol FAQs

How is Kygenesis different from other kidney supplements?

Kygenesis formulas are developed by Naturopaths with deep clinical and research experience in kidney health. The ingredients are pure, premium and many are concentrated extracts for up to 10X more potency.

When will I start seeing results?

Each individual responds differently to the supplements in Kygenesis.

Before taking Kygenesis, be sure you have the results from blood work. Repeat the blood tests after 3-4 months of consistently taking Kygenesis daily.

We also recommend keeping a daily symptom diary. A sense of wellbeing, improved energy and mental clarity are often the first noticeable improvements.

Kygenesis supplements are most effective when combined with a diet that promotes kidney health, exercise and meditation or other practices that reduce stress.

Is there anyone who should not take Kygenesis?

Kygenesis is made from ingredients that are deemed safe for the general population when taken as recommended. If you have a pre-existing health condition, are pregnant or lactating, consult a healthcare professional before using any nutritional supplement.

Can I take Kygenesis with my prescription medications?

Some pharmaceuticals cannot be taken with specific nutritional supplements. If you are taking any medication we recommend speaking to your professional health care provider or emailing customer support at [email protected].

Can I use Kygenesis supplements to safely reduce or eliminate my medication?

Kygenesis is formulated to support kidney function but cannot recommend that you substitute these supplements for prescribed medication or recommended over-the-counter medication. Please consult with your qualified health-care practitioner for advice on your medication.

Why is it necessary to take Kygenesis daily over the long-term?

The nutrients and herbs in Kygenesis support kidneys under stress. Over time, with age and accumulated stress on our organs, normal kidney function can be increasingly challenged. Your kidneys work hard every day. Kygenesis is formulated to deliver the daily support that helps maintain normal function.

If I take a higher dose, will I see improvements in my health faster?

Kygenesis supplements are calibrated for maximum efficacy and safety at the recommended dose — not above. Please follow the dosage guidelines or as directed by your healthcare professional.

What are the shipping and handling costs?

Domestic US and international shipping costs vary depending on the shipping method you choose at checkout. You will see the shipping costs in your checkout process and can adjust your shipping method before placing your order.

Where is Kygenesis made?

Kygenesis is prepared in New York, in a multi-award-winning FDA registered facility, certified GMP by NSF International through independent audits. The chemists and technicians operate to the highest standards of quality.

What if I have more questions?

Please email our Customer Service at [email protected]