Niacinamide, also known as nicotinamide or vitamin B3, is a water-soluble vitamin that plays a vital role in many biological processes in the body. It is an essential nutrient that our body needs but cannot produce on its own, so we need to obtain it from our diet or supplements. Niacinamide is a precursor to…
What is Nitric Oxide? Nitric oxide (NO) is a colourless gas that has been found to help dilate blood vessels and stimulate certain hormones such as insulin and human growth hormone. It has also been found to exert numerous effects on the kidneys, heart and vasculature. Reduced NO has been associated with aging, kidney, cardiovascular…
What are Oxalates? Oxalic acid is an organic compound found in many plants, including leafy green vegetables, cocoa, fruit, sweet potato, currants and spinach just to name a few. Generally, the oxalate content in plants is at its highest in the leaves followed by the seeds then at its lowest in the stems. The concentration…
Both vitamins K and D are fat-soluble nutrients, both of which play a role in calcium metabolism. Vitamin D deficiency (VDD) is widespread and has become a major healthcare issue. The prevalence of VDD is estimated to be more than a billion people worldwide. It has been reported that in individuals with CKD, VDD is…
An overall incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) are expected as we see the prevalence of obesity and diabetes increase throughout the world. We now know, risk factors associated with NAFLD are also associated with the development of chronic kidney disease (CKD). Research has found, patients with NAFLD are at a higher…
What is Carnosine? Carnosine (β-alanyl-l-histidine) is a natural ACE inhibitor and a powerful antioxidant. Made up of two amino acids (alanine and histidine), it acts as a free radical scavenger protecting cells against free radical damage. It was first discovered in the 1900s by Russian chemist V.S. Gulewitch. Carnosine is naturally produced in the body…
It may or may not come as a surprise to you, but yes, there is a link between gum, heart and kidney disease. This is largely about inflammation and oxidative stress caused by gum disease. Research within this area of health has shown that patients with chronic kidney disease who also suffer from periodontitis are…
This article follows on from my previous article on ‘The Role of the Mitochondria in Chronic Disease’. Today, I will speak exclusively on the role mitochondria play in kidney disease. Just to recap and keep you up to date, the main job of mitochondria is to produce energy through a process called oxidative phosphorylation. Mitochondria…
Today, I’m going to take you through the role mitochondria play in the process of chronic disease. Mitochondria are best known for their participation in cellular respiration via oxidative phosphorylation. This reaction produces ATP (adenosine triphosphate), a form of cellular energy. Mitochondria participate in important metabolic pathways and regulate various important cellular functions. Due to…
Eucommia bark has been used by herbalists for more than 2500 years specifically for its ability to support depleted kidney energy, a symptom often talked about in Ancient Chinese Medicine. In the ancient art of Chinese medicine, the kidneys are responsible for our vitality, or how much energy we have on a day-to-day basis. If…
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