MOTS-C (mitochondrial open-reading-frame of the twelve S rRNA-C) is a recently discovered peptide that is believed to play a significant role in regulating metabolism and aging. It is a mitochondrial-encoded peptide that is released into the bloodstream and regulates insulin sensitivity and energy metabolism. Research suggests that MOTS-C may have potential therapeutic benefits in treating…
Kidney disease is a complex condition that affects millions of people worldwide. One of the key factors that contribute to the development and progression of kidney disease is the regulation of phosphorus in the body. Phosphorus is an essential mineral that plays a critical role in many cellular processes, but excessive levels of phosphorus in…
Niacinamide, also known as nicotinamide or vitamin B3, is a water-soluble vitamin that plays a vital role in many biological processes in the body. It is an essential nutrient that our body needs but cannot produce on its own, so we need to obtain it from our diet or supplements. Niacinamide is a precursor to…
Terminalia Arjuna & CKD Terminalia arjuna, also known as Arjuna, is a plant that is widely used in Ayurvedic medicine to treat various ailments, including kidney disease and cardiovascular disease. Recent scientific research has been conducted to explore the potential benefits of T. arjuna on kidney and heart health, and the findings are promising. Chronic…
What is Nitric Oxide? Nitric oxide (NO) is a colourless gas that has been found to help dilate blood vessels and stimulate certain hormones such as insulin and human growth hormone. It has also been found to exert numerous effects on the kidneys, heart and vasculature. Reduced NO has been associated with aging, kidney, cardiovascular…
What is NAD or Nicotinamide adenine dinucleotide? Nicotinamide adenine dinucleotide (NAD) plays a vital role in the process of energy metabolism and production, and plays a key role in mitochondrial function. Its functions range from redox reactions, and it is also known as a central player in multiple cellular signalling pathways, organ resilience and longevity….
Both vitamins K and D are fat-soluble nutrients, both of which play a role in calcium metabolism. Vitamin D deficiency (VDD) is widespread and has become a major healthcare issue. The prevalence of VDD is estimated to be more than a billion people worldwide. It has been reported that in individuals with CKD, VDD is…
What is Carnosine? Carnosine (β-alanyl-l-histidine) is a natural ACE inhibitor and a powerful antioxidant. Made up of two amino acids (alanine and histidine), it acts as a free radical scavenger protecting cells against free radical damage. It was first discovered in the 1900s by Russian chemist V.S. Gulewitch. Carnosine is naturally produced in the body…
What are Senescent Cells? The definition senescent literally means the condition or process of deterioration with age. In biology, senescence is a process by which a cell ages and then permanently stops dividing, but does not die. Senescent cells are undead cells (that should be dead) that lack a protein that tells them when to…
Parsley (Petroselinum crispum) Parsley would have to be one of the world’s most popular culinary herbs. Grown for its tasty green leaves, parsley provides a source of vitamin C, iron and vitamin A. It is a member of the carrot family and native to the Mediterranean. The word parsley comes from the Greek, meaning ‘rock…
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