MOTS-C (mitochondrial open-reading-frame of the twelve S rRNA-C) is a recently discovered peptide that is believed to play a significant role in regulating metabolism and aging. It is a mitochondrial-encoded peptide that is released into the bloodstream and regulates insulin sensitivity and energy metabolism. Research suggests that MOTS-C may have potential therapeutic benefits in treating…
Kidney disease is a complex condition that affects millions of people worldwide. One of the key factors that contribute to the development and progression of kidney disease is the regulation of phosphorus in the body. Phosphorus is an essential mineral that plays a critical role in many cellular processes, but excessive levels of phosphorus in…
Cardiovascular disease (CVD) and chronic kidney disease (CKD) are major health problems affecting millions of people worldwide. According to the World Health Organization (WHO), CVD is the leading cause of death globally, responsible for approximately 17.9 million deaths annually, while CKD affects around 10% of the world’s population. Both CVD and CKD share many common…
Terminalia Arjuna & CKD Terminalia arjuna, also known as Arjuna, is a plant that is widely used in Ayurvedic medicine to treat various ailments, including kidney disease and cardiovascular disease. Recent scientific research has been conducted to explore the potential benefits of T. arjuna on kidney and heart health, and the findings are promising. Chronic…
Both vitamins K and D are fat-soluble nutrients, both of which play a role in calcium metabolism. Vitamin D deficiency (VDD) is widespread and has become a major healthcare issue. The prevalence of VDD is estimated to be more than a billion people worldwide. It has been reported that in individuals with CKD, VDD is…
What is Carnosine? Carnosine (β-alanyl-l-histidine) is a natural ACE inhibitor and a powerful antioxidant. Made up of two amino acids (alanine and histidine), it acts as a free radical scavenger protecting cells against free radical damage. It was first discovered in the 1900s by Russian chemist V.S. Gulewitch. Carnosine is naturally produced in the body…
What are Senescent Cells? The definition senescent literally means the condition or process of deterioration with age. In biology, senescence is a process by which a cell ages and then permanently stops dividing, but does not die. Senescent cells are undead cells (that should be dead) that lack a protein that tells them when to…
This article follows on from my previous article on ‘The Role of the Mitochondria in Chronic Disease’. Today, I will speak exclusively on the role mitochondria play in kidney disease. Just to recap and keep you up to date, the main job of mitochondria is to produce energy through a process called oxidative phosphorylation. Mitochondria…
What are Peptides? Peptides are made up of a cluster of up to 20 amino acids, which are the building blocks of protein. A cluster of over 20 amino acids is typically known as a protein, and a cluster of fewer than 20 amino acids is known as a peptide. Peptides work in the body…
Lavender is a common herb that can be found in many gardens and is often renowned for its strong and fragrant aroma coupled with its beautiful purple flowers. This herb is not only a lovely herb to have in the garden, but it also has great therapeutic properties that have a long history of traditional…
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